For the creation of a virtual 3D creature it is necessary an underlying structure that provides to it some desired capabilities. One of our main research objectives is creating a virtual 3D creature that resembles human behavior in an actual environment. In this paper, we propose a cognitive architecture inspired in the recent findings of the neuroscience which will represent the underlying structure for implementing virtual 3D creatures with human-like capabilities. Those virtual creatures will be useful to study human behavior in actual environments by means of simulations. Felipe Rodríguez, Francisco Galvan, Félix Ramos, Erick Castellanos, Gregorio García, Pablo Covarrubias: A Cognitive Architecture Based on Neuroscience for the Control of Virtual 3D Human Creatures. Brain Informatics 2010: 328-335. LNAI 6334, ISSN 0302-9743. ISBN 978-3-642-15313-6.